Document Type
Poster Presentation
Publication Date
12-2014
Department
Pharmacy
Abstract
Objective: As a result of the heightened reactivity fructose demonstrates compared to glucose and our current knowledge of glucose advanced glycation end-products, the aim of this research was to further elucidate the proinflammatory pathways involved in the response to fru-AGE exposure, including the effects of fru-AGEs on cell-surface receptor expression. We hypothesized that once microglia were activated in response to fru-AGE exposure, there would be an increase in the expression of RAGE and TLR4 to facilitate the proinflammatory cascade.
Publication Information
Stryker, Matthew; Blackley, Regina; and Lull, Melinda E., "Altered Cell-surface Receptor Levels Result from Fructose Advanced Glycation End Product-Induced Inflammation" (2014). Doctoral External Publications. Paper 3.
https://fisherpub.sjf.edu/doctoral_ext_pub/3
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Comments
Poster presented at at American Society of Health Systems Pharmacy Midyear Clinical Meeting in Anaheim, California, in December 2014.