The Association Between Early Exposure to Antibiotics and Childhood Asthma Incidence

Authors

Victoria Fischer, St. John Fisher UniversityFollow

Abstract

This review examines the association between early exposure to antibiotics and the incidence of asthma in childhood, highlighting significant public health concerns related to antibiotic overuse. The misuse of antibiotics not only contributes to antibiotic resistance but may also impact long-term health outcomes, particularly respiratory diseases like asthma. Emerging evidence suggests that early antibiotic exposure may disrupt gut microbiota, altering immune responses and increasing the risk of asthma development. A systematic review of twenty-seven studies identified a significant correlation between antibiotic use in infancy and subsequent asthma diagnoses. However, there remains a need for further research to delineate the extent of this association, as much of the existing literature primarily focuses on antibiotic resistance. This review analyzes four quantitative studies that investigate the relationship between antibiotic exposure in early life and asthma incidence. Findings indicate a dose-dependent relationship, with increased asthma risk correlating with the frequency and type of antibiotics prescribed during infancy. These results underscore the necessity for healthcare providers to exercise caution when prescribing antibiotics to infants, promoting awareness of potential long-term health implications. Further research is essential to deepen our understanding of this association, which can inform clinical practices and pediatric healthcare strategies aimed at reducing asthma incidence among children.

Recommended Citation

Fischer, Victoria (2024) "The Association Between Early Exposure to Antibiotics and Childhood Asthma Incidence," Soaring: A Journal of Undergraduate Research: Vol. 2024, Article 6.
Available at: https://fisherpub.sjf.edu/soaring/vol2024/iss2/6