TAC-1 depletion in C. Elegans using RNAi
Document Type
Poster Presentation
Publication Date
4-25-2025
Keywords
fsc2025
Abstract
RNA (single stranded DNA) was fed to microscopic worms (nematodes) to inhibit a target gene. In this case, tac-1. Tac-1 is a microtubule associated-protein, and heavily involved in the cell cycle (cell division). When tac-1 is depleted in worms, the phenotype is observed and these observations can pave the way to understand TACC related cancer in humans. TACC related cancer has been seen in almost 90% of thyroid and breast cancers via over expression or under expression of TACC proteins.
Publication Information
Cafferelli, Aleescia, "TAC-1 depletion in C. Elegans using RNAi" (2025). Fisher Showcase 2025. Paper 20.
https://fisherpub.sjf.edu/fsc2025/20
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Comments
Student poster presented at the 2025 Fisher Showcase, St. John Fisher University, April 25, 2025.