TAC-1 depletion in C. Elegans using RNAi

Document Type

Poster Presentation

Publication Date

4-25-2025

Keywords

fsc2025

Abstract

RNA (single stranded DNA) was fed to microscopic worms (nematodes) to inhibit a target gene. In this case, tac-1. Tac-1 is a microtubule associated-protein, and heavily involved in the cell cycle (cell division). When tac-1 is depleted in worms, the phenotype is observed and these observations can pave the way to understand TACC related cancer in humans. TACC related cancer has been seen in almost 90% of thyroid and breast cancers via over expression or under expression of TACC proteins.

Comments

Student poster presented at the 2025 Fisher Showcase, St. John Fisher University, April 25, 2025.

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