IL-1 Generated Subsequent to Radiation-induced Tissue Injury Contributes to the Pathogenesis of Radiodermatitis

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Conference Proceeding

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Radiodermatitis is a condition in which the skin becomes inflamed and the epidermis can break down following radiation injury. In this study we developed a murine model of radiodermatitis where the skin is selectively injured by high-energy electron radiation. Using this model we investigated the interleukin-1 (IL-1) pathway in the development of radiodermatitis.



Presented at the American Society for Radiation Oncology 54th Annual Meeting in Boston, Massachusetts, October 2012.

Abstract included in the meeting's proceedings: a special issue of International Journal of Radiation Oncology*Biology*Physics. Volume 84, Issue 3, Supplement, 1 November 2012, Page S679.

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